Steroid Hormone-regulated let-7b Mediates Cell Proliferation and Basigin Expression in the Mouse Endometrium
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چکیده
منابع مشابه
MicroRNA let-7b-regulated epidermal stem cell proliferation in hypertrophied anal papillae
The present study investigated the role of epidermal stem cell-expressed microRNA let-7b in the pathogenesis of hypertrophied anal papillae. Hypertrophied anal papillae were examined for the presence of epidermal stem cells. Epidermal stem cells were identified using flow cytometry and immunofluorescent staining for the cell surface markers, integrin α6 and integrin β1 subunits. Expression leve...
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Neural stem cell self-renewal and differentiation is orchestrated by precise control of gene expression involving nuclear receptor TLX. Let-7b, a member of the let-7 microRNA family, is expressed in mammalian brains and exhibits increased expression during neural differentiation. However, the role of let-7b in neural stem cell proliferation and differentiation remains unknown. Here we show that...
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Genotoxic stressors, such as radiation, induce cellular damage that activates pre-programmed repair pathways, some of which involve microRNAs (miRNA) that alter gene expression. The let-7 family of miRNA regulates multiple cellular processes including cell division and DNA repair pathways. However, the role and mechanism underlying regulation of let-7 genes in response to stress have yet to be ...
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ژورنال
عنوان ژورنال: Journal of Reproduction and Development
سال: 2011
ISSN: 0916-8818,1348-4400
DOI: 10.1262/jrd.11-018e